The patient is a woman who had lumpectomy and radiation on the left for breast cancer treatment. She did not desire an implant, muscle flap surgery, or completion mastectomy. After discussion with the patient’s oncology team, the patient elected to undergo serial fat grafting of the left breast with right breast matching mastopexy. After 3 fat grafting sessions, the breast was soft enough to allow nipple relocation. While this reconstruction was not traditional, fat grafting only in a radiated breast is considered well accepted practice and the patient is happy with her result.